𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Requirement of the MASH-1 transcription factor for neuroendocrine differentiation of thyroid C cells

✍ Scribed by Lanigan, Thomas M. ;DeRaad, Shannon K. ;Russo, Andrew F.

Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
179 KB
Volume
34
Category
Article
ISSN
0022-3034

No coin nor oath required. For personal study only.

✦ Synopsis

Thyroid C cells are neural crestcitonin and serotonin were still expressed in cultured derived neuroendocrine cells that can acquire features mature C cells that no longer express MASH-1, demsimilar to serotonergic neurons. Based on developmental and phenotypic markers, we have previously onstrating that MASH-1 is not directly required for proposed that C cells and serotonergic enteric neurons the expression of these two markers. Hence, MASHarise from a common sympathoadrenal progenitor. In 1 is required to establish the C-cell phenotype and this report, we genetically examined this relationship supports the model that C cells lie in the neuronal using mice lacking the mammalian achaete-scute differentiation pathway of the sympathoadrenal homologue 1 (MASH-1) transcription factor, since neural crest. α­§ 1998

πŸ“œ SIMILAR VOLUMES

Regulation of hippocampal neuronal diffe
Regulation of hippocampal neuronal differentiation by the basic helix-loop-helix transcription factors HES-1 and MASH-1
✍ Paul Castella; John A. Wagner; Michael Caudy πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 244 KB πŸ‘ 2 views

HES-1 is a vertebrate homologue of the Drosophila basic helix-loop-helix (bHLH) protein Hairy, a transcriptional repressor that negatively regulates neuronal differentiation. HES-1 expression in neuronal precursors precedes and represses the expression of the neuronal commitment gene MASH-1, a bHLH

TheAFT1 Transcriptional Factor is Differ
TheAFT1 Transcriptional Factor is Differentially Required for Expression of High-Affinity Iron Uptake Genes inSaccharomyces cerevisiae
✍ CASAS, CELIA; ALDEA, MARTÍ; ESPINET, CARME; GALLEGO, CARME; GIL, ROSARIO; HERRER πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 545 KB

High-affinity iron uptake in Saccharomyces cerevisiae involves the extracytoplasmic reduction of ferric ions by FRE1 and FRE2 reductases. Ferrous ions are then transported across the plasma membrane through the FET3 oxidase-FTR1 permease complex. Expression of the high-affinity iron uptake genes is

Neurotrophins facilitate neuronal differ
Neurotrophins facilitate neuronal differentiation of cultured neural stem cells via induction of mRNA expression of basic helix-loop-helix transcription factors Mash1 and Math1
✍ Hisanori Ito; Aki Nakajima; Hiroshi Nomoto; Shoei Furukawa πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 376 KB

## Abstract Neurogenesis is promoted by basic helix‐loop‐helix (bHLH) transcription factors Mash1, Math1, or NeuroD but suppressed by another set, Hes1 and Hes5. It remains unknown what kinds of extracellular signals are involved in their regulation; therefore, the effects of neurotrophins on the e

Interaction of the transcription factor
Interaction of the transcription factor Sp1 with the nuclear pore protein p62 requires the C-terminal domain of p62
✍ InnOc Han; Mark D. Roos; Jeffrey E. Kudlow πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 166 KB πŸ‘ 2 views

The transcription factor Sp1 plays an important role in the expression of many cellular genes. In studies of proteins that associate with Sp1, a 62-kDa glycoprotein was found in immunoprecipitates of Sp1. This protein was detected in these immunoprecipitates by the monoclonal antibody, RL2, which wa