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Requirement of neuronal- and cardiac-type sodium channels for murine sinoatrial node pacemaking

✍ Scribed by Ming Lei; Sandra A. Jones; Jie Liu; Matthew K. Lancaster; Simon S.-M. Fung; Halina Dobrzynski; Patrizia Camelliti; Sebastian K. G. Maier; Denis Noble; Mark R. Boyett

Book ID: 110112912
Publisher: Cambridge University Press
Year: 2004
Tongue: English
Weight: 492 KB
Volume: 559
Category: Article
ISSN: 0022-3751
DOI: 10.1113/jphysiol.2004.068643

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## Abstract In myelinated axons, voltage‐gated sodium channels specifically cluster at the nodes of Ranvier, while voltage‐gated potassium channels are located at the juxtaparanodes. These characteristic localizations are influenced by myelination. During development, Nav1.2 first appears in the pr