Requirement of nerve growth factor for development of substance P-containing sensory neurones
β Scribed by Otten, Uwe; Goedert, Michel; Mayer, Norbert; Lembeck, Fred
- Book ID
- 109719649
- Publisher
- Nature Publishing Group
- Year
- 1980
- Tongue
- English
- Weight
- 212 KB
- Volume
- 287
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/287158a0
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Nerve growth factor interacts with responsive cells by binding to cell surface membrane receptors. There are two different receptors on both embryonic sensory and sympathetic neurons, a highβaffinity (type I) receptor and a lowerβaffinity (type II) receptor. Sequestration, which we have
The response to nerve growth factor (NGF) of two sensory neuron populations of the trigeminal nerve was studied in chick embryos. NGF promoted neuronal survival and cellular hypertrophy in the Gasserian ganglia with minimal effect on the neuron population of the mesencephalic trigeminal nucleus. NGF