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Requirement of free carboxyl groups for the anticoagulant activity of heparin

✍ Scribed by Anil Agarwal; Isidore Danishefsky

Book ID
119036223
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
497 KB
Volume
42
Category
Article
ISSN
0049-3848

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πŸ“œ SIMILAR VOLUMES

Chemical reduction of carboxyl groups in
Chemical reduction of carboxyl groups in heparin abolishes its vasodilatory activity
✍ Edgar J. Paredes-Gamero; ValquΓ­ria P. Medeiros; Marcelo A. Lima; Camila M. Accar πŸ“‚ Article πŸ“… 2012 πŸ› John Wiley and Sons 🌐 English βš– 319 KB

## Abstract Previous studies have shown that heparin induces vascular relaxation via integrin‐dependent nitric oxide (NO)‐mediated activation of the muscarinic receptor. The aim of this study was to identify the structural features of heparin that are necessary for the induction of vasodilatation.