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Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis

✍ Scribed by Dixon, R. A. F.; Diehl, R. E.; Opas, E.; Rands, E.; Vickers, P. J.; Evans, J. F.; Gillard, J. W.; Miller, D. K.

Book ID
109762463
Publisher
Nature Publishing Group
Year
1990
Tongue
English
Weight
361 KB
Volume
343
Category
Article
ISSN
0028-0836

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## Abstract ## Objective To explore the modulation of 5‐lipoxygenase–activating protein (FLAP) and 5‐lipoxygenase (5‐LOX) expression in human osteoarthritic (OA) chondrocytes, their relative implications in leukotriene B~4~ (LTB~4~) production, the effect of different factors on this system, and t