Reprogramming towards pluripotency requires AID-dependent DNA demethylation

AID in reprogramming: Quick and efficien

AID in reprogramming: Quick and efficient : Identification of a key enzyme called AID, and its activity in DNA demethylation, may help to overcome a pivotal epigenetic barrier in reprogramming somatic cells toward pluripotency

✍ Wenbin Deng 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 57 KB

## Abstract Current methods of reprogramming differentiated cells into induced pluripotent stem cells remain slow and inefficient. In a recent report published online in __Nature__, Bhutani __et al.__1 developed a cell fusion strategy, achieving quick and efficient reprogramming toward pluripotency