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Repression of the human immunodeficiency virus type 1 promoter by the human KRAB domain results in inhibition of virus production

✍ Scribed by O Herchenröder; J.C Hahne; W.K.-H Meyer; H.-J Thiesen; J Schneider


Book ID
114148509
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
550 KB
Volume
1445
Category
Article
ISSN
0167-4781

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## Abstract The effect of __trans__‐acting factors on __cis__‐acting DNA elements on the HIV‐1 promoter are the principal determinant regulating transcriptional activation and repression. Host factors that limit viral replication can contribute to the emergence and maintenance of proviral reservoir