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Repression of PXR-mediated induction of hepatic CYP3A gene expression by protein kinase C

โœ Scribed by Xunshan Ding; Jeff L. Staudinger


Book ID
113487470
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
166 KB
Volume
69
Category
Article
ISSN
0006-2952

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Ozone is one of the most common air pollutants humans routinely inhale. We have previously shown that in vitro ozone exposure induces the DNA-binding activities of NFk B and NF-IL6 as well as the expression of interleukin 8 in respiratory epithelial cells. In this study, we investigated intracellula