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Repression of protein translation and mTOR signaling by proteasome inhibitor in colon cancer cells

✍ Scribed by William Ka Kei Wu; Viviana Volta; Chi Hin Cho; Ya Chun Wu; Hai Tao Li; Le Yu; Zhi Jie Li; Joseph Jao Yiu Sung


Book ID
116298813
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
461 KB
Volume
386
Category
Article
ISSN
0006-291X

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## Abstract In the treatment of colon cancer, the development of resistance to apoptosis is a major factor in resistance to therapy. New molecular approaches to overcome apoptosis resistance, such as selectively upregulating proapoptotic proteins, are needed in colon cancer therapy. In a mouse mode