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Repression of hepatic δ-aminolevulinate synthase by heme and metalloporphyrins: Relationship to inhibition of heme oxygenase

✍ Scribed by Edward E. Cable; Julia W. Cable; Herbert L. Bonkovsky


Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
976 KB
Volume
18
Category
Article
ISSN
0270-9139

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The serum protein hemopexin is considered to have a major role in the mechanism of the uptake of heme by hepatocytes by means of a heme-hemopexin receptor. Therefore, we examined in primary cultures of adult rat and embryonic chick hepatocytes whether the presence of hemopexin would affect the heme-