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Repression of arginine-glycine transamidinase activity by dietary creatine

โœ Scribed by James B. Walker


Book ID
115788214
Publisher
Elsevier Science
Year
1959
Weight
117 KB
Volume
36
Category
Article
ISSN
0006-3002

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Six fully conserved arginine residues (R129, R131, R235, R291, R319, and R340) closely grouped in the nucleotide binding site of rabbit muscle creatine kinase (rmCK) were mutated; four to alanine and all six to lysine. Kinetic analyses in the direction of phosphocreatine formation showed that all fo