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Representation of noncovalent interactions in protein structures

✍ Scribed by Xavier de la Cruz; Jesús Reverter; Ignacio Fita


Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
524 KB
Volume
10
Category
Article
ISSN
0263-7855

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A novel mass spectrometry-based methodology using electrospray ionization (ESI) is described for the detection of protein-protein [interferon (IFN)-γ dimer] and protein-ligand [ras-guanosine diphosphate (GDP)] noncovalent interactions. The method utilizes ESI from aqueous solution at appropriate pH.