Application of electrospray mass spectro
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Eric C. Huang; Birendra N. Pramanik; Anthony Tsarbopoulos; Paul Reichert; Ashit
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Article
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1993
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Elsevier Science
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English
⚖ 741 KB
A novel mass spectrometry-based methodology using electrospray ionization (ESI) is described for the detection of protein-protein [interferon (IFN)-γ dimer] and protein-ligand [ras-guanosine diphosphate (GDP)] noncovalent interactions. The method utilizes ESI from aqueous solution at appropriate pH.