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Reporter-gene systems for the study of G-protein-coupled receptors

✍ Scribed by Stephen J Hill; Jillian G Baker; Stephen Rees


Book ID
117786444
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
301 KB
Volume
1
Category
Article
ISSN
1471-4892

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Efficient screening of ligands interacting with Gprotein-coupled receptors is central for modern drug development. Here, we describe an optimized reporter vector primarily intended for use in reporter cell lines expressing such receptors. The construct consists of a synthetic enhancer containing 9Ψ‹