Nucleosomes activate NF-κB in endothelia
✍
Jerome E. Tanner
📂
Article
📅
2004
🏛
John Wiley and Sons
🌐
French
⚖ 250 KB
## Abstract Solid tumors often exhibit regions undergoing apoptosis and necrosis, also referred to as “aponecrosis”, juxtaposed to sites of active angiogenesis. We explored whether nucleosomes resulting from aponecrosis induced the angiogenic factor IL‐8 in vascular endothelial cells. Results indic