Report of an intrapulmonary solitary fibrous tumor: Fine-needle aspiration cytologic findings, clinicopathological, and immunohistochemical features

✍ Scribed by R.A. Caruso; F. LaSpada; M. Gaeta; I. Minutoli; C. Inferrera

• Publisher: John Wiley and Sons
• Year: 1996
• Tongue: English
• Weight: 406 KB
• Volume: 14
• Category: Article
• ISSN: 8755-1039
• DOI: 10.1002/(sici)1097-0339(199602)14:1<64::aid-dc13>3.0.co;2-b

✦ Synopsis

The authors describe a rare case of intrapulmonary solitary f ibrous tumor (SFT). Morphologically, the tumor showed a disorganized or ')atternless" arrangement ofplump to spindle cells in a collagenous stroma. Tumor cells were immunoreactive for vimentin, but not for keratin, carcinoembryonic antigen, epithelial membrane antigen, factor-VIII related antigen, S-100 protein, desmin, and actin. These immunohistochemical findings sug- gested fibroblastic diferentiation, in keeping with the putative submesothelial origin of the tumor. The problems concerning the fine-needle aspiration (FNA) preoperative diagnosis of SFT are briefly discussed.