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Reply to the letter by R. Buscall

โœ Scribed by Tsuneo Okubo


Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
101 KB
Volume
138
Category
Article
ISSN
0021-9797

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Dr. Vinogradov points out that propidium iodide (PI) binding data do not always reflect accurate genome size values. PI binding can be influenced by the chromatin conformation. In addition, PI is not DNA specific and pretreatment of samples with RNase can affect the fluorescence intensity in an unpr