✦ LIBER ✦

Reply to letter by Dr. Macey

✍ Scribed by A. Martin; F.R. Barber

Book ID: 115713230
Publisher: Elsevier Science
Year: 1971
Tongue: English
Weight: 45 KB
Volume: 5
Category: Article
ISSN: 0004-6981
DOI: 10.1016/0004-6981(71)90109-0

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Dr. Vinogradov points out that propidium iodide (PI) binding data do not always reflect accurate genome size values. PI binding can be influenced by the chromatin conformation. In addition, PI is not DNA specific and pretreatment of samples with RNase can affect the fluorescence intensity in an unpr