𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Reply to F. Giannelli: Theoretical expectations for deletional mutations in Duchenne muscular dystrophy

✍ Scribed by Grimm, T. ;Danieli, G. A. ;Müller, C. R. ;Opitz, John M.

Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
107 KB
Volume
31
Category
Article
ISSN
0148-7299

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Theoretical expectations for deletional
Theoretical expectations for deletional mutations in Duchenne muscular dystrophy
✍ Giannelli, Francesco ;Opitz, John M. 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 89 KB 👁 1 views

The letter by on the theoretical expectations for deletional mutations in Duchenne muscular dystrophy (DMD) is very misleading. The authors base al1 of their arguments and calculations on the hypothesis that, in DMD, deletions occur exclusively or aimost exclusively by homologous recombination, and

Theoretical expectations for deletional
Theoretical expectations for deletional mutations in duchenne muscular dystrophy
✍ Grimm, Tiemo ;Danieli, Gian A. ;Muller, Clemens R. ;Neri, Giovanni ;Reynolds, Ja 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 327 KB 👁 1 views

## To the Editor: In a population, when equilibrium between mutation and selection is reached, a fraction (x) of individuals affected by an X-linked recessive lethal disorder is due to new mutations [Haldane, 19351. Being p, the mutation rate in female germ cells, and v, the mutation rate in male