Reply to Comments on “Highly Antimalaria-Active Artemisinin Derivatives: Biological Activity Does Not Correlate with Chemical Reactivity”

✍ Scribed by Richard K. Haynes

• Publisher: John Wiley and Sons
• Year: 2005
• Tongue: English
• Weight: 66 KB
• Volume: 44
• Category: Article
• ISSN: 0044-8249
• DOI: 10.1002/anie.200462723

✦ Synopsis

In light of the discussion on C10‐substituted derivatives of the antimalarial agent artemisinin in the preceding correspondence article which relates to his earlier work, R. K. Haynes reiterates here that there is no correlation between the ability of artemisinins to react with heme‐ or non‐heme‐Fe^II^ and their antimalarial activity.