Reply to Cigarette smoking and glutathione S-transferase M1 polymorphism associated with risk for uterine cervical cancer
β Scribed by Charu Lata Jindal; Himanshu Goel
- Book ID
- 109007326
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 124 KB
- Volume
- 36
- Category
- Article
- ISSN
- 1341-8076
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Glutathione S-transferases (GSTs) belong to a superfamily of detoxification enzymes that provide critical defences against a large variety of chemical carcinogens and environmental toxicants. GSTs are present in most epithelial tissues of the human gastrointestinal tract. We investigated association
## Abstract ## Objective To determine whether the relationship between smoking and disease severity in women with rheumatoid arthritis (RA) is associated with polymorphism at the glutathione Sβtransferase (GST) M1 locus. ## Methods Genotyping for GSTM1 was carried out using polymerase chain reac
Individual response to oxidative stress, due to exposure to asbestos fibres plays a significant role in the malignant pleural mesothelioma (MPM) etiology. The differential impact on MPM risk of polymorphic alleles of glutathione-S-transferases (GSTs) and manganese superoxide dismutase (MnSOD/SOD2) g