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Reply: Blockade of Janus kinase 2 signaling ameliorates mouse liver damage due to ischemia and reperfusion

โœ Scribed by Ricky Harminder Bhogal; Simon C. Afford

Book ID
102468646
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
43 KB
Volume
16
Category
Article
ISSN
1527-6465

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โœฆ Synopsis

Liver Transplantation 1 does indeed show that Janus kinase 2 (JAK2) inhibitors reduce lipopolysaccharide (LPS)-mediated mouse hepatoma cell apoptosis. They cited previous work showing that primary mouse hepatocytes and mouse hepatoma cells respond to LPS stimulation by expressing functional toll-like receptor 4.

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