Reply anion effects on calcium metabolism: A caveat

✍ Scribed by Uriel S. Barzel

• Publisher: American Society for Bone and Mineral Research
• Year: 2010
• Tongue: English
• Weight: 97 KB
• Volume: 11
• Category: Article
• ISSN: 0884-0431
• DOI: 10.1002/jbmr.5650111223

✦ Synopsis

s postulate "that the nature of the accompanying anion is the major determining factor of the effects of sodium salts and calcium salts" is a sentiment we share, but with the following caveat concerning calcium. Given the nature of the typical Western diet, calcium accompanied by a metabolizable anion such as carbonate is an efficacious form of calcium for promoting calcium retention, but in persons already consuming an alkaline diet such as vegetarians, it is not known whether more alkalinity is necessary or even desirable. Further, excess metabolizable anion intake, such as with sodium bicarbonate or calcium carbonate, is associated with development of the milk-alkali syndrome.t!' which is becoming a more frequent occurrence.(2)