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Replicative Forms of TT Virus DNA in Bone Marrow Cells

✍ Scribed by Hiroaki Okamoto; Masaharu Takahashi; Tsutomu Nishizawa; Akio Tawara; Yoshiki Sugai; Toshiaki Sai; Takeshi Tanaka; Fumio Tsuda


Book ID
115585571
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
149 KB
Volume
270
Category
Article
ISSN
0006-291X

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## Abstract The TT virus (TTV), a member of a family of human viruses related to the __circoviridae__ viruses, was associated initially with acute and chronic liver diseases. TTV consists of a single‐stranded, circular DNA genome of 3.8 kilobases (kb) and at least three open reading frames (ORFs).

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## Abstract The TT virus (TTV) is a non‐enveloped, single‐stranded, circular, DNA virus, first isolated from a patient with hepatitis of unexplained etiology. The much deliberated pathological role of the virus continues to be conjectural in the absence of a suitable in vitro replication model. So