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Replication of varicella-zoster virus is influenced by the levels of JNK/SAPK and p38/MAPK activation

✍ Scribed by Rahaus, M.

Book ID
120411763
Publisher
Society for General Microbiology
Year
2004
Tongue
English
Weight
304 KB
Volume
85
Category
Article
ISSN
0022-1317

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ORF61 protein of Varicella–zoster virus
ORF61 protein of Varicella–zoster virus influences JNK/SAPK and p38/MAPK phosphorylation
✍ Markus Rahaus; Nathalie Desloges; Manfred H. Wolff πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 244 KB

Recently, it was demonstrated that the Varicellazoster virus (VZV) infection led to an activation of MAP kinases. The viral protein encoded by ORF61 is a major effector of JNK/SAPK and p38/MAPK phosphorylation. ORF61 shows homology to HSV-1 ICP0, a multifunctional protein that influences the activit