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Replication of Colicin E1 Plasmid DNA in Cell Extracts: II. Selective Synthesis of Early Replicative Intermediates

✍ Scribed by Yoshimasa Sakakibara and Jun-Ichi Tomizawa

Book ID
123652249
Publisher
National Academy of Sciences
Year
1974
Tongue
English
Weight
784 KB
Volume
71
Category
Article
ISSN
0027-8424

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Replication of the colicin E1 plasmid in
Replication of the colicin E1 plasmid in extracts of Escherichia coli: Uncoupling of leading strand from lagging strand synthesis
✍ Staudenbauer, Walter L. ;Scherzinger, Eberhard ;Lanka, Erich πŸ“‚ Article πŸ“… 1979 πŸ› Springer 🌐 English βš– 722 KB

The replication of the ColEl plasmid was studied in extracts from E. coli dnaG mutants. It was found that the synthesis of the complementary strands of ColEl DNA can be carried out in these extracts in two consecutive steps: (1) synthesis of the leading L strand independent of the dnaG function, and