Amylin-induced in vivo insulin resistanc
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S. J. Koopmans; A. D. M. van Mansfeld; H. S. Jansz; H. M. J. Krans; J. K. Radder
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Article
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1991
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Springer
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English
⚖ 800 KB
Amylin is a polypeptide of 37 amino acids, predominantly synthesized in pancreatic Beta cells. The peptide was suggested to be dysregulated in Type 2 (non-insulin-dependent) diabetes mellitus and it antagonized certain actions of insulin in vitro in rat muscle. This led to speculation that amylin is