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Replication-defective mutants of mouse cytomegalovirus elicit protective immunity

✍ Scribed by Clive Sweet

Book ID: 117771596
Publisher: Elsevier Science
Year: 1999
Tongue: English
Weight: 81 KB
Volume: 12
Category: Article
ISSN: 1386-6532
DOI: 10.1016/s1386-6532(99)00024-4

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## Abstract Previously, we showed that two temperature‐sensitive mutants of murine cytomegalovirus (__tsm__5 and __tsm__30) expressed immediate‐early (IE‐1), early (E‐1), and late (gB) phase genes in the tissues of immunocompetent Balb/c mice, yet failed to produce infectious progeny virus in any t