Different test results have been reported for the same were obtained in both cell types, CHL cells sometimes chemicals in two in vitro chromosome aberration had higher aberration levels and survived at higher test systems, CHL cells tested by a Japanese protocol doses than CHO cells would tolerate.
โฆ LIBER โฆ
Replicate flasks are not necessary for in vitro chromosome-aberration assays in CHO cells
โ Scribed by Keith A. Soper; Sheila M. Galloway
- Book ID
- 113252973
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 862 KB
- Volume
- 312
- Category
- Article
- ISSN
- 0165-1161
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## Abstract International guidelines for cytotoxicity limits for the in vitro chromosomal aberration assay require reductions in cell growth of greater than 50%. This sets no upper limit on toxicity and there is concern about the number of false or irrelevant results obtained in the aberration assa