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Repertoire of antibodies against type 1 poliovirus in human sera

✍ Scribed by Gennady Rezapkin; Alexander Neverov; Elena Cherkasova; Emmanuel Vidor; Andrei Sarafanov; Diana Kouiavskaia; Eugenia Dragunsky; Konstantin Chumakov


Book ID
113768474
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
597 KB
Volume
169
Category
Article
ISSN
0166-0934

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Inhibitory antibodies to the reverse transcriptase (RT) of human immunodeficiency virus type-1 (HIV-1) can be used to block the life cycle of the virus. We have isolated five different human single chain Fv (ScFv) antibodies specific for HIV-1 RT from an antibody phage display library. Three of thes