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Repeated measures in clinical trials: simple strategies for analysis using summary measures

โœ Scribed by Stephen Senn; Lynda Stevens; Nish Chaturvedi

Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
142 KB
Volume
19
Category
Article
ISSN
0277-6715

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โœฆ Synopsis

The summary measures approach to analysing repeated measures is described. The circumstances under which it can be advantageous to use such measures are considered. Strategies for baseline adjustment where there are multiple baselines are examined, as is the choice of appropriate summary statistic. A compromise trend/mean measure, regression through the origin, is proposed as being useful under some circumstances. An analysis using this measure is illustrated with a suitable example.

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