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Repeated confidence intervals for group sequential clinical trials

✍ Scribed by Jennison, Christopher; Turnbull, Bruce W.


Book ID
123238531
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
735 KB
Volume
5
Category
Article
ISSN
0197-2456

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## Abstract In self‐designing clinical trials, repeated confidence intervals are derived for the parameter of interest where the results of the independent study stages are combined using the generalized inverse chi‐square‐method. The confidence intervals can be calculated at each interim analysis