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Repeated cannabinoid administration increases indices of noradrenergic activity in rats

✍ Scribed by M.E. Page; V.C. Oropeza; S.E. Sparks; Y. Qian; A.S. Menko; E.J. Van Bockstaele


Book ID
113841243
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
298 KB
Volume
86
Category
Article
ISSN
0091-3057

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The effects of prolonged treatment of rats with zimelidine, 5, 12.5, and 25 ~tmol/kg PO twice daily for 2 weeks, on the accumulation of 14C-5-hydroxytryptamine (I#C-5-HT) and 3H-noradrenaline (3H-NA) in hypothalamic slices were studied. The concentrations of 5-HT and 5-hydroxyindoleacetic acid (5-HI