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Repeated amphetamine: reduced dopamine neuronal responsiveness to apomorphine but not quinpirole

✍ Scribed by David K. Pitts; Arthur S. Freeman; Mark D. Kelland; Louis A. Chiodo

Book ID
115882640
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
345 KB
Volume
162
Category
Article
ISSN
0014-2999

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Using in vivo extracellular single-cell recording and microiontophoresis, we compared the responsiveness of medial prefrontal cortex (mPFC) neurons (layers V-VI) to dopamine and glutamate in rats that had received repeated amphetamine or saline injections. Neurons from amphetamine-pretreated rats sh