Repeat isolated limb perfusion with TNFα and melphalan for recurrent limb melanoma after failure of previous perfusion
✍ Scribed by E.M. Noorda; B.C. Vrouenraets; O.E. Nieweg; A.N. van Geel; A.M.M. Eggermont; B.B.R. Kroon
- Book ID
- 116442570
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 136 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0748-7983
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Background. Hyperthermic isolated limb perfusion (HILP) has been shown to be effective for locoregional metastases or local recurrent disease. Locoregional recurrences after previous HILP is an unsolved problem. Methods. HILP with cisplatin, 20-30 mg/l perfused limb volume, was performed in seven p
## Background: This retrospective study evaluated the benefit of using tumor necrosis factor (tnf) and melphalan administered via an isolated limb perfusion (ilp) in a series of patients with metastatic melanoma who failed initial ilp with chemotherapeutics. ## Methods: Seventeen patients with ex