Repair of the two cis-syn diastereoisomers formed between 3-carbethoxy-psoralen and thymidine in yeast cells, followed by a chemical method

Repair of the two diastereoisomer photoa

Repair of the two diastereoisomer photoadducts formed between 7-methylpyrido(3,4-c)psoralen (MePyPs) and thymidine in yeast cells: A chemical approach

✍ M. Dardalhon; A. Moysan; D. Averbeck; P. Vigny 📂 Article 📅 1993 🏛 Elsevier Science 🌐 English ⚖ 649 KB

When analysing the repair of psoralen plus UVA-induced photoadducts in DNA, it must be realized that, in most cases, different isomers are formed. The monofunctional psoralen derivative 7-methylpyrido(3,4-c)psoralen (MePyPs) is known for its high antiproliferative activity at the cellular level and