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Repair of oxidative DNA damage is delayed in the Ser326Cys polymorphic variant of the base excision repair protein OGG1

✍ Scribed by Kershaw, R. M.; Hodges, N. J.

Book ID
126454247
Publisher
Oxford University Press
Year
2012
Tongue
English
Weight
596 KB
Volume
27
Category
Article
ISSN
0267-8357

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## Abstract Oxidative damage represents the most significant insult to organisms because of continuous production of the reactive oxygen species (ROS) in vivo. Oxidative damage in DNA, a critical target of ROS, is repaired primarily via the base excision repair (BER) pathway which appears to be the