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Repair of DNA lesions in chromosomal DNA: Impact of chromatin structure and Cockayne syndrome proteins

✍ Scribed by Maria Fousteri; Anneke van Hoffen; Hana Vargova; Leon H.F. Mullenders


Book ID
116410425
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
127 KB
Volume
4
Category
Article
ISSN
1568-7864

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## Abstract Bulky DNA damage is corrected by the nucleotide excision repair (NER) pathway. Although the core biochemical mechanism of NER is understood, details including lesion recognition and repair in the context of chromatin remain to be elucidated. As more data become available, the complexity