Reoxygenation of hypoxic HUVECs in human sera augments nuclear NF-κB translocation and expression of vascular cell adhesion molecule-1 (VCAM-1): Inhibition with anti-human C5 therapy

Induction of vascular cell adhesion mole

Induction of vascular cell adhesion molecule-1 expression by IL-4 in human aortic smooth muscle cells is not associated with increased nuclear NF-κB levels

✍ Paul S. Wright; Judith R. Cooper; Keith E. Kropp; Steven J. Busch 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 244 KB 👁 2 views

Vascular cell adhesion molecule-1 (VCAM-1) and intercellular adhesion molecule-1 (ICAM-1) are upregulated in vascular endothelial and smooth muscle cells by cytokines produced at sites of inflammation. The cytokine profile for induction of VCAM-1, however, is different for the two cell types. Tumor