Reoxygenation in the RIF-1 tumor
β Scribed by Mary J. Dorie; Robert F. Kallman
- Publisher
- Elsevier Science
- Year
- 1984
- Tongue
- English
- Weight
- 692 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0360-3016
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Near-infrared radiation from a NdYAG laser at 1,064 nm was used interstitially or superficially to induce hyperthermia in RIF-1 tumors in C,H male mice. A single 600-pm quartz fiber with a 0.5-cm cylindrical diffusor or a weakly diverging microlens at its distal end was used to deliver laser energy
## Abstract Treatment of RIFβ1 solid tumors with 5βfluorouracil (5βFU, 100 or 200 mg/kg, ip) caused substantial regression of the tumors, with regrowth initiated on Day 6 (100 mg/kg) or Day 9 (200 mg/kg). Blood perfusion in the tumor, estimated by uptake of ^86^Rb^+^, was significantly increased af