Reorganization of gap junctions after focused ultrasound blood–brain barrier opening in the rat brain
✍ Scribed by Alonso, Angelika; Reinz, Eileen; Jenne, Jürgen W; Fatar, Marc; Schmidt-Glenewinkel, Hannah; Hennerici, Michael G; Meairs, Stephen
- Book ID
- 109871563
- Publisher
- Nature Publishing Group
- Year
- 2010
- Tongue
- English
- Weight
- 529 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0271-678X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Blood–brain barrier opening using focused ultrasound and microbubbles has been experimentally established as a noninvasive and localized brain drug delivery technique. In this study, the permeability of the opening is assessed in the murine hippocampus after the application of focused u
## Abstract The use of contrast agents for neuroimaging is limited by the blood‐brain barrier (BBB), which restricts entry into the brain. To administer imaging agents to the brain of rats, intracarotid infusions of hypertonic mannitol have been used to open the BBB. However, this technically chall