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Reoperation in metastasizing medullary thyroid carcinoma: Is a tumor stage-oriented approach justified?

✍ Scribed by Oliver Gimm; Henning Dralle


Book ID
117220884
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
786 KB
Volume
122
Category
Article
ISSN
0039-6060

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## Abstract In multiple endocrine neoplasia syndrome Type 2 (MEN2), medullary thyroid carcinoma (MTC) and pheochromocytoma (PC) are associated with hereditary activating germ‐line mutations in the __RET__ proto‐oncogene. Also in a large percentage of sporadic MTCs and PCs, somatic __RET__ mutations