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Renoprotective effects of mineralocorticoid receptor blockade in heminephrectomized (pro)renin receptor transgenic rats

✍ Scribed by Yuki Mizuguchi; Atsuhiro Ichihara; Yasufumi Seki; Mariyo Sakoda; Asako Kurauchi-Mito; Tatsuya Narita; Kenichiro Kinouchi; Kanako Bokuda; Hiroshi Itoh


Book ID
108940680
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
378 KB
Volume
37
Category
Article
ISSN
0305-1870

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The aim of this study was to assess the effect of HS-142-1, a recently discovered specific antagonist of endogenous natriuretic peptides, on systemic hemodynamics, renal function, and the renin-aldosterone system in rats with cirrhosis and ascites. The study consisted of three protocols, each includ