𝔖 Bobbio Scriptorium
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Renin activity in rat choroid plexi: effects of water-deprivation and hypovolemia

✍ Scribed by J. M. Kapsha; W. B. Severs

Book ID
105415846
Publisher
Springer
Year
1983
Tongue
English
Weight
236 KB
Volume
39
Category
Article
ISSN
1420-682X

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The effects of temporary water deprivation for 48 h on the pharmacokinetics and pharmacodynamics of bumetanide were examined after intravenous (i.v.) administration of bumetanide, 8mg kg-' to control and water deprived rats (n=7). The values of AUC, t,,, and MRT increased 79.0, 417, and 633 per cent