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Renal vasoconstrictor and pressor responses to angiotensin IV in mice are AT1a-receptor mediated

✍ Scribed by R. YANG; T. WALTHER; F. GEMBARDT; I. SMOLDERS; P. VANDERHEYDEN; A.L. ALBISTON; S. CHAI; A.G. DUPONT


Book ID
116548865
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
64 KB
Volume
137
Category
Article
ISSN
0167-5273

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Angiotensin II (Ang II) given centrally produces an increase in blood pressure and motivation to drink. The physiological mechanisms that mediate the pressor response include release of vasopressin (AVP) and activation of the sympathetic nervous system. Using 2 new Ang II receptor antagonists, we we