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Renal tubular dysgenesis, absent nipples, and multiple malformations in three brothers: A new, lethal syndrome

✍ Scribed by Hisama, Fuki M.; Reyes-Mugica, Miguel; Wargowski, David S.; Thompson, Kate J.; Mahoney, Maurice J.


Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
47 KB
Volume
80
Category
Article
ISSN
0148-7299

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✦ Synopsis


We report on three brothers with renal tubular dysgenesis and absent nipples, each also had other malformations including preauricular pits and a preauricular tag, branchial clefts, choanal atresia, pulmonary lobation anomaly, ventricular septal defect, type IIB interrupted aortic arch, absent gallbladder, absent thymus, parathyroid gland, accessory spleen, imperforate anus, clinodactyly, and broad digits and small nails. All three infants died neonatally. This pattern of clinical malformations appears to be a previously unreported syndrome. Am.