Renal tubular damage after renal stone treatment

✍ Scribed by Trinchieri, A. ;Mandressi, A. ;Zanetti, G. ;Ruoppolo, M. ;Tombolini, P. ;Pisani, E.

• Book ID: 104689454
• Publisher: Springer
• Year: 1988
• Tongue: English
• Weight: 292 KB
• Volume: 16
• Category: Article
• ISSN: 0300-5623
• DOI: 10.1007/bf00261965

✦ Synopsis

50 patients were studied with respect to renal tubular damage related to open operative, percutaneous and extracorporeal shock wave treatment of renal stones. Preoperative and postoperative urinary N-acetyl-glucosaminidase (NAG) levels were measured as a marker of renal damage. There was no significant evidence of renal tubular damage in patients who underwent a conventional or percutaneous nephrolithotomy; urinary NAG excretion was significantly increased after ischaemic surgery. After extracorporeal shock wave lithotripsy (ESWL) serum NAG levels increased, probably because a damage of the white blood cells in cutaneous and renal circulation, but a slight increase of urinary NAG excretion could suggest a mild renal tubular damage especially in case of more than 2,000 shocks.