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Renal tubular cell injury and serum phospholipase A2 activity in acute pancreatitis

✍ Scribed by Dr J. M. Grönroos; A. J. Hietaranta; T. J. Nevalainen


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
253 KB
Volume
79
Category
Article
ISSN
0007-1323

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We investigated the mechanism of phospholipase A 2 (PLA 2 ) activation in response to the P2 receptor agonist ATP in rat thyroid FRTL-5 cells. The PLA 2 activity was determined by measuring the release of [ 3 H]-arachidonic acid (AA) from prelabeled cells. ATP evoked a dose-and time-dependent AA rel