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Renal proximal tubular cells acquire resistance to cell death stimuli in mice with hereditary tyrosinemia type 1

✍ Scribed by Luijerink, Marjanka C.; van Beurden, Ellen A.C.M.; Malingre, Helga E.M.; Jacobs, Saskia M.M.; Grompe, Markus; Klomp, Leo W.J.; Berger, Ruud; van den Berg, Inge E.T.

Book ID: 109066523
Publisher: Nature Publishing Group
Year: 2004
Tongue: English
Weight: 386 KB
Volume: 66
Category: Article
ISSN: 0085-2538
DOI: 10.1111/j.1523-1755.2004.00788.x

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Chronic liver disease in murine hereditary tyrosinemia type 1 induces resistance to cell death

✍ Arndt Vogel; Inge E.T. van den Berg; Muhsen Al-Dhalimy; John Groopman; Ching-Nan 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 508 KB

The murine model of hereditary tyrosinemia type 1 (HT1) was used to analyze the relationship between chronic liver disease and programmed cell death in vivo. In healthy fumarylacetoacetate hydrolase deficient mice (Fah(-/-)), protected from liver injury by the drug 2-(2- nitro-4-trifluoromethylbenzo