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Renal Na+-phosphate cotransporter gene expression in X-linked Hyp and Gy mice

✍ Scribed by Tenenhouse, Harriet S; Beck, Laurent


Book ID
109884367
Publisher
Nature Publishing Group
Year
1996
Tongue
English
Weight
784 KB
Volume
49
Category
Article
ISSN
0085-2538

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X-linked hypophosphatemia is a genetic bone disease in humans and mice. Two closely linked mutations in mice, Hyp and G y , cause low plasma phosphate and a rachitic and osteomalacic bone disease. Because of the controversy as to whether Gy is a good model for X-linked hypophosphatemia, the phenotyp