RENAL MEDULLARY CARCINOMA AND ABL GENE AMPLIFICATION
โ Scribed by SIMPSON, L; HE, X; PINS, M; HUANG, X; CAMPBELL, S; YANG, X; PERLMAN, E; BERGAN, R
- Book ID
- 123516911
- Publisher
- Lippincott Williams and Wilkins
- Year
- 2005
- Tongue
- English
- Weight
- 692 KB
- Volume
- 173
- Category
- Article
- ISSN
- 0022-5347
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Background. Renal medullary carcinoma (RMC), an extremely rare tumour of the kidney, carries a dismal prognosis, with no reports to date of significant response to chemotherapy or radiotherapy. A case of this tumour in a male child, who showed a dramatic response to chemotherapy, is described. Proce
## Abstract ## BACKGROUND Renal medullary carcinoma is a rare kidney tumor with highly aggressive behavior. This tumor occurs exclusively in young patients with sickle cell trait or disease. To the authors' knowledge, very little is known to date regarding the underlying molecular genetics of this